Povital

Vitamin B1, B6 & B12 Indications Vitamin B1, B6 & B12 is indicated for the treatment of vitamin B1, B6 & B12 deficiency syndrome. It is also indicated for the supportive treatment of neuritis & non-inflammatory diseases of the nerves, e.g.- Diabetic neuropathy Peripheral neuralgin Lumbago Myalgia Optic neuritis Sciatica Facial neuralgia Intercostal neuralgia Spinal pain Pharmacology Vitamin B1 promotes healthy neurons, boosts mood, and strengthens the heart by converting carbs, fatty acids, and amino acids into energy. Vitamin B6 aids in the formation of red blood cells (RBCs), aids in the production of proteins in cells, manufactures neurotransmitters such as serotonin, and releases stored forms of energy, aids in the prevention of CVS diseases and stroke, aids in the treatment of depression, and aids in the treatment of insomnia. Vitamin B12 is necessary for cell replication and RBC synthesis, as well as preventing anemia, depression, nerve pain, numbness, and tingling, and lowering the risk of heart disease. The vitamin components are well absorbed when taken orally. It is found in breast milk and is broadly dispersed in most tissues. Thiamine is usually found as diphosphate within the cell. Thiamine is not retained in the body in significant proportions, and excess amounts are eliminated in the urine as intact thiamine or as metabolites. Following oral administration, pyridoxine, pyridoxal, and pyridoxamine are rapidly absorbed from the GIT and transformed to the active forms of pyridoxal phosphate and pyridoxamine phosphate. They are primarily stored in the liver, where they are oxidized to 4-pyridoxic acid and other inactive metabolites that are eliminated in the urine. Dosage & Administration Tablet: 1-3 Tablets per day or as advised by the physician. Injection: In severe (acute) cases: 1 injection daily until the acute symptoms subside or taken as advised by the physician. In mild cases: 1 injection 2-3 times per week. Ampoules are preferably injected intramuscularly. Use in children: There is no information on the use of this drug in children. Contraindications Vitamin B1, Vitamin B6 and Vitamin B12 is contraindicated in patients on levodopa therapy, and in patients with hypersensitivity to any of the ingredients of the preparation. Side Effects Although it is generally well-tolerated, allergic responses have been reported in a few occasions. Pregnancy & Lactation Although oral tablet form is preferred, injection is not advised during pregnancy or lactation due to the presence of benzyl alcohol. Precautions & Warnings Cyanocobalamin should not be given to patients who have subacute spinal degeneration. Cyanocobalamin is not a good type of vitamin B12 for treating visual neuropathies caused by high cyanocobalamin levels in the blood. Therapeutic Class Specific combined vitamin preparations Storage Conditions Protect from light and moisture by storing in a cool, dry place below 30°C. Keep out of children's reach. Pharmaceutical Name ACI Limited